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In brief, 1 ml of both samples was placed on a dialysis semipermeable membrane that had previously been put in phosphate buffer (pH 6.8 for 24 h) and fixed over the lower opening of a glass tube (2 cm diameter)

doi:10.3389/fphar.2023.1205207 Teixeira LCR, Luizon MR, Gomes KB

doi: 10.1016/j.jmgm.2020.107666 90 ReddyBYMillerDMTsaoH

Alteration of V beta usage and cytokine production of CD4+ TCR beta beta homodimer T cells by elimination of Bacteroides vulgatus prevents colitis in TCR alpha-chain-deficient mice

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In summary, while small observational uses of alpha-lipoic acid in pregnancy have not reported acute problems, the absence of comprehensive safety data means ALA is not routinely recommended for pregnant or lactating women